Postdoc estudiando la relación entre genotipo y fenotipo en el Institute of Integrative Biology (ETH Zurich)

Oferta compartida por Nuria

The Computational Biology group in the Institute of Integrative Biology at ETH Zurich, led by Joshua L. Payne, is hiring a postdoctoral researcher with funding for up to two years. The group is broadly interested in evolution, particularly in the relationship between genotype and phenotype, and the role of mutation in the generation of adaptive phenotypic variation. We study these topics at multiple scales of information transmission from DNA to protein, with an emphasis on transcriptional regulation and translation. A predefined project centered around these topics is available, but we are also open to defining a project around the applicant's interests.

The group is currently made up of four PhD students and one postdoc. Interdisciplinarity is key to our research and this shows in our team composition, with backgrounds in physics, biophysics, computer science, developmental biology, and evolution. We value diversity - at present we represent four continents - and we strive to maintain a 50-50 gender balance. Applicants from underrepresented groups are especially encouraged to apply.

The successful candidate will have experience in some form of computational science, a passion for evolutionary biology, and a Ph.D. in a related discipline (math, physics, bioinformatics, computer science, life sciences). Fluency in a major programming language is essential, as is the ability to work both autonomously and cooperatively within an interdisciplinary, multicultural team. Experience modeling evolutionary processes or analyzing large-scale biological datasets, such as from functional genomics assays or massively parallel sequence-to-function assays, is a plus. We will begin considering applications immediately with the aim of a September 1st, 2021 start date. Later start dates are
also possible.

To be considered for the position, please send a single pdf file to joshua.payne@env.ethz.ch including your CV, publication list, a single-paged statement of research interests, and contact information for 2-3 academic references. Please write Postdoc2021 in the subject line.

Representative papers from the group:
Cano et al. (2021) "Mutation bias shapes the spectrum of adaptive substitutions." bioRxiv
Rozhonova & Payne (2021) "Little evidence the standard genetic code is optimized for resource conservation." bioRxiv
Majic & Payne (2020) "Enhancers facilitate the birth of de novo genes and gene integration into regulatory networks." Molecular Biology and Evolution, 37, 1165-1178.
Payne et al. (2019) "Transition bias influences the evolution of antibiotic resistance in Mycobacterium tuberculosis." PLoS Biology, 17, e3000265.
Payne & Wagner (2019) $B!H (BThe causes of evolvability and their evolution. $B!I (B Nature Reviews Genetics, 20, 24-38.

Group website: joshualevipayne.com

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¿Quieres investigar en Japón? Echa un vistazo a esta convocatoria para 60 postdocs

Oferta compartida por Nuria


RIKEN is currently accepting applications for the FY 2022 Special Postdoctoral Researcher (SPDR) Program, from young, creative, independent researchers who will be a powerful force in furthering RIKEN's research activities.

The involvement of creative young scientists is critical in pioneering new frontiers of science and technology. RIKEN’s Special Postdoctoral Researcher Program is a program to foster the development of researchers who will become internationally active in the future, and provides creative young scientists with the opportunity to be involved in autonomous and independent research on a topic of their own choosing that is in line with RIKEN objectives and research fields. The total number of hiring is about 60.

Deadline for registering basic information: Apr 8, 2021 (Japan Std Time)
Deadline for revising or uploading application documents and letters of reference: 5PM, April 15 Thursday, 2021 (Japan Std Time)

Research fields (in theoretical biology) to work at iTHEMS:

• Ecology & Evolution（w/ Dr. Ryosuke Iritani）
• Biological Networks（w/ Dr. Takashi Okada）
• Biological Clocks（w/ Dr. Gen Kurosawa）
• Population Genetics（w/ Dr. Jeffrey Fawcett）
• Computational Virology（w/ Dr. Catherine Beauchemin）

Applicants must fulfill all five conditions given below:

1. Be prepared to independently and responsibly pursue a research topic.
2. Have a PhD awarded on or after January 1, 2016, or expect to be awarded a PhD by the date of hire. Note: Those with PhDs acquired prior to December 31, 2015, may also apply if there was a lapse in their research activity, and if subtracting this period of non-research activity will allow them an equivalency that meets the above requirement. If applicable, please fill the details (specific reasons and period) in the application form. RIKEN’s screening committee will determine whether the period of lapse is justifiable after the deadline for submitting the application. Examples of acceptable periods of lapse: maternity leave, childcare leave, and working in private industry in a non-research capacity.
3. Able to start work in FY2022 (April 1, 2022 to March 31, 2023)
4. The employee's period of fixed-term employment cannot exceed 10 years from the initial date of hire (or 10 years from April 1, 2013 for fixed-term employees already at RIKEN prior to this date).
5. Those who have previously participated in the SPDR and FPR programs are NOT eligible to apply.

For more details on the application procedure and deadlines visit: https://www.riken.jp/en/careers/programs/spdr/career2022/
iTHEMS website: https://ithems.riken.jp/en
Contact information: https://ithems.riken.jp/en/contact

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¿Te interesa el intercambio de fluidos? Echa un vistazo a esta oferta de postdoc para estudiar insectos sociales

Oferta compartida por Nuria

We are looking for a postdoc to join the Social Fluids Lab (http://leboeuflab.com/) studying collective control of physiology from either a molecular or computational/physics perspective.

The Social Fluids Lab:
Our lab takes an integrative approach to studying how behavior evolves. We study socially exchanged fluids and how they can be used for consensus building and be co-opted by evolution to influence physiology and behavior. We use social insects as a model system because many engage in a mouth-to- mouth fluid exchange called trophallaxis, wherein they transmit endogenously produced molecules that can influence receivers. In many species that engage in this behavior, every individual in the colony is connected through this network of fluid exchange. The exchanged fluid is rich with proteins, hormones, RNA and small molecules (LeBoeuf et al. 2016 eLife). Some of these components, when fed to larvae by trophallaxis, can influence developmental fate and timing! This provides a means for how some social insect communities can collectively decide on the colony’s developmental progression – by sending cues and signals over the social circulatory system.

Our lab uses machine learning approaches in both evolutionary proteomics and long-term automated tracking of behavior and fluorescence in ant colonies to answer our questions about the evolution of behavior. We are a relatively young research group building this field of socially exchanged materials.

Lab values
Creativity, interdisciplinarity, collaboration, open source, open access, inclusiveness, team mentality.

You:
We are looking for a primarily molecular and/or primarily computational postdoc to join our group. The ideal candidate is collaborative, committed and passionate about their research; they should fit (broadly) one of the two phenotypes detailed below.

• Phenotype 1 (molecular): How does the social circulatory system circumvent the longevity-fecundity trade-off? You are comfortable with molecular and biochemical approaches (e.g. in situ hybridization, protein purification, developing assays, microscopy). You are interested in behavior, superorganismal physiology and how socially transmitted components can influence receivers.
• Phenotype 2 (computational): Quantitative behavioral tracking of different kinds of individuals different individuals (adults and larvae) in the same network and fluorescent tracking of flow over the social network. You are comfortable coding in python and have experience with image and/or network analysis. You might not be a biologist by training but rather an engineer, computer scientist or physicist. You are interested in collective behavior and distributed problem-solving.

Your specific project will depend on your interests but will certainly focus on socially exchanged fluids and collective developmental control in social insects. If you think you have yet another phenotype that would fit well with the Social Fluids labor for another type of position, write to Adria.

Positions
Start dates are flexible, aiming at first half of 2021. Position is currently funded for 2 years but could be extended depending on circumstances, for example, a candidate coming with or applying for
their own funding.

Submission
Applications (in English) should include a statement on your background and motivation to join our research group*, CV (including an annotated list of publications (preprints included) wherein you describe your contribution to the works), and the names and contact details of two references.

Applications should be sent as a single pdf to adrialeboeuf@gmail.com

DEADLINE: February 1st, 2021. Applications will be reviewed until positions are filled.

*This part is absolutely key to your application: What sparked your interest in our group? What scientific questions are you motivated by that align with ours? What research skills would you bring?

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