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12 de diciembre de 2017

PhD position in coastal dynamics, Monash University, Australia

G'day, we are seeking a talented applicant for a fully funded PhD position in coastal dynamics funded by an Australian Research Council Discovery Award. The project is a collaboration between Monash University, The University of Cambridge (UK) and Birkbeck University, London. The student will be based at Monash University (School of Earth, Atmosphere and Environment) in Melbourne, Australia, but will require some travel to the UK.

The project focusses on the response of vegetated foreshores to sea level rise. The low elevation coastal zone contains 13% of the Australian population and is subject to intensive agriculture and urbanisation. Accelerating sea level rise is thus a major societal concern and its impacts on shorelines must be accurately determined. This Australian-UK collaboration aims to improve Australia?s capacity to predict changing shoreline position with sea level rise, better understand the role of vegetation in foreshore stabilisation and identify under what conditions the shoreline might suddenly shift landwards.



The successful applicant will apply field based wave and sedimentation measurements with remote sensing (drone and satellite) data within a numerical modelling framework to determine the forcings affecting shoreline retreat with sea level rise in Australia, in order to improve predictive capacity.



The candidate should hold, or expect to shortly obtain, at least an Honours 1 degree or equivalent in physical geography, oceanography, environmental science or other relevant disciplines.



Applications are now open. If you wish to be considered for the position, the application deadline is 12 noon on Thursday 21 December 2017, with interviews expected to be held mid-January.



Please send a cover letter detailing your motivation and research experience along with a CV to Dr Ruth Reef, ruth.reef@monash.edu Feel free to contact me for further information.



The funded position is open to high achieving domestic and international students and will provide a stipend and a living allowance according to the Monash University fee and scholarship schedule.


https://www.monash.edu/graduate-research/future-students/support/stipend

11 de diciembre de 2017

Simposio: "Evolutionary Quantitative Genetics in the Wild" (Registro gratis para estudiantes)

DEADLINE DEC 31 for FREE STUDENT REGISTRATION

The AGA is offering multiple free registration slots to graduate students who submit an abstract for the American Genetic Association Symposium, "Evolutionary Quantitative Genetics in the Wild".

For all others, early registration is $150 and includes receptions, meals,
and complimentary membership in the American Genetic Association with
subscription to Journal of Heredity.

AGA symposia are small, friendly gatherings, and provide wonderful
opportunities for students and researchers to engage with one another and
share their science. This spring's meeting will take place March 23-25,
2018, at the University of Toronto, Canada. It will focus on quantitative
genetics of fitness-related traits in an evolutionary context across
diverse species.

We will open with a reception on Friday night, and our Key Distinguished
Lecturer, Loeske Kruuk, will lead off a full day of talks on Saturday. A
poster session reception is planned for Saturday night. Finally, a half
day of talks will be presented on Sunday.

Registration is open! For all details, visit http://www.theaga.org.

Best wishes,

Anne Bronikowski, 2017 AGA President
John Stinchcombe, Local Host and Co-Organizer

_____

Speakers:

Wilhemine Key Distinguished Lecture by Loeske Kruuk (Australian Natl U.) ~
"Quantitative Genetics of Fitness in Wild Populations"

David Coltman, U. Alberta ~ "Architecture of quantitative traits in
bighorn sheep"

Jeff Conner, Mich State ~ "Mechanisms of rapid adaptation"

Lynda Delph, Indiana U. ~ "Sex-specific selection drives sexual dimorphism
in correlated characters"

Ned Dochtermann, U. N Dakota ~ "Is behavior fundamentally different from
other types of traits: behavioral heritabilities and genetic correlations
in crickets"

Kathleen Donohue, Duke U. ~ "Regulating life-cycle phenology through
developmental arrest: Seed dormancy and plant life cycles in seasonal
environments"

Fred Janzen, Iowa State ~ "Evolutionary quantitative genetics of sex
determination in freshwater turtles"

Adam Jones, U. Idaho ~ "Epistasis in the wild"

Emily Josephs, UCDavis & Mich State ~ "Detecting polygenic adaptation
in domesticated and wild plants"

Andrew McAdam, U. Guelph ~ "Maternal effects in North American red
squirrels"

Joel McGlothlin, Virgina Tech ~ "Quantitative genetics of sexual
dimorphism in brown anoles"

Mike Morrissey, U. St Andrews ~ "Development and non-additive genetic
variation"

Leonie Moyle, Indiana U. ~ "Intraspecific polymorphism for quantitative
traits and interspecific isolating barriers in wild tomato"

Julia Saltz, Rice U. ~ "Gene-environment correlation: implications for
evolutionary quantitative genetics"

Jon Slate, U. Sheffied ~ "Genomic prediction in a wild mammal"

John Stinchcombe, U. Toronto ~ "Evolutionary genetics in wild and
invasive plants"

Cynthia Weinig, U. Wyoming ~ "Genetic underpinnings of plant-microbe
interactions and their role in adaptation"

Jason Wolf, U. Bath ~ "A genomic perspective on multivariate evolution"

Anjanette Baker <theaga@theaga.org>

10 de diciembre de 2017

Oferta de doctorado en biologia celular estudiando enfermedades neurodegenerativas

The German Center for Neurodegenerative Diseases (DZNE) is a unique non-university research center which is dedicated to the subject dementia and all its areas, as well as other neurodegenerative diseases. The center compasses the full spectrum of fundamental research through population sciences to health care research. The DZNE stands for excellence in research and science management, translation of scientific results into practice, interdisciplinarity and internationalization. It is a research center within the Helmholtz Organization of German research centers. With over 1000 employees from 55 nations, spread over 9 sites, the DZNE is one of the national and international leading research centers in its research field.

The DZNE in Bonn is looking for a

PhD student (f/m) - Code 1522/2017/12

to join the research group of Dr Melania Capasso.

The Capasso lab is interested in elucidating pathways regulating immune cell function, both in adaptive and innate immune cells, as well as their impact in neurodegenerative diseases.

We are seeking an enthusiastic PhD student to work on signalling pathways regulating inflammation in innate immune cells, as well as how they change in ageing. In particular, the project will centre on elucidating molecular mechanisms regulating inflammation downstream the mTOR pathway.

Your profile:

Well-organised and pro-active PhD candidate with a degree in a relevant biomedical subject, preferably in the field of immunology and/or cell signalling. Previous experience with molecular biology techniques, such as RNA work or cloning would be a bonus. Showing initiative and flexibility, also regarding working hours when required, will be desirable qualities.
We offer:
• An interesting and challenging task in a Research Center that works on the future topics of health research.
• An international environment characterized by a strong focus on Science and Research.
• A high potential for the individual development of our employees.
• Targeted personell development.
• Employment, payment and social benefits are consistent with those at other research institutes.
You will obtain special skills and knowledge for your scientific qualification during your activities at DZNE.
The DZNE is an equal opportunity employer. The DZNE is committed to employing disabled individuals and especially encourages them to apply.
Please apply via the following link:

https://jobs.dzne.de/de/jobs/115/form

9 de diciembre de 2017

PhD or postdoc proposal to work with parakeet movements and habitat use

We are looking for candidates who would be interested in submitting a personal application for a parakeet research project to the 1st of February call of the FWO, the Flemish Fund for Scientific Research. This could be either for a PhD fellowship, or a postdoc fellowship. Funding is not guaranteed as the call is quite competitive, but we would be happy to support the candidate in writing a strong application. In particular, we have some ideas for a project on parakeet movements using the latest GPS tracking technology, possibly combined with remote sensing methodologies. The main focus would be on parakeet movements and habitat use.

As the selection is based on the applicant’s CV as well as project quality, suitable candidates should have a very strong track record (for PhD fellowships (only EU/EER!): excellent study grades, if possible a publication; for postdoc fellowships: a strong publication record, and preferably already some international mobility).

Potential candidates can contact us for more information at erik.matthysen@uantwerpen.be and/or diederik.strubbe@ugent.be. Information on the call can be found at http://www.fwo.be/en/fellowships-funding/.
Yours sincerely,

Erik Matthysen
Diederik Strubbe

8 de diciembre de 2017

Postdoc: Experimental evolution (Switzerland)

Postdoctoral Position: Experimental evolution in response to chronic malnutrition in Drosophila

A postdoctoral position is available in Tad Kawecki's group at the
Department of Ecology and Evolution, University of Lausanne,
Switzerland. We are looking for a qualified and motivated researcher to
study genomic and molecular/physiological bases of evolutionary
adaptation to nutrient-poor diet in Drosophila. The project will take
advantage of a long-term evolutionary experiment, in which replicate
populations have been maintained on an extremely poor larval diet for
over 230 generations. These populations have evolved a variety of life
history, physiological and behavioral adaptations to this nutritional
stress, as well as modified interactions with pathogenic and beneficial
bacteria. Genome resequencing and gene expression profiling point to
candidate genes and pathways that may mediate these evolutionary
changes. The general aim of the project is to verify some of these
candidates and gain a deeper insight into the underlying mechanisms.
Possible approaches include genetic mapping, detailed analysis of gene
expression and molecular phenotypes and manipulative experiments using
Drosophila genetic toolkit. For more information see Erkosar et al.
(2017) mBio 8:e01496-01417 and Vijendravarma et al. (2015) Ecology
Letters 18:1078–1086.

The project requires a combination of experimental and
statistical/genomics skills, interest in adaptive evolution, and
independence in designing and carrying our experiments. Experience with
Drosophila or knowledge of insect physiology are a plus but are not
required. The research group is English-speaking and no-preexisting
knowledge of French is required, but learning basic French would make
living in Lausanne easier. In addition to work on the project, the
holder of the position is expected to contribute up to 25% of the
working time to teaching activities, including supervision of master
students.

The candidate is expected to start within the first four months of 2018.
The position is at 100% (lower rate is negotiable e.g. for family
reasons), with the annual salary of about CHF 80,000 (about US$ 80,000
or Euro 68,000). The position is initially offered for one year; a
possible extension for additional two years will depend on the funding
situation and the progress of the project.

Lausanne is a medium-sized city on the shores of Lake Geneva, surrounded
by a wine growing region recognized as a UNESCO World Heritage Site, and
within one hour of the Alps. It offers a great variety of cultural,
recreational and outdoor opportunities. The Department of Ecology and
Evolution (www.unil.ch/dee) is a vibrant research community, with 20
research groups, over 100 graduate students and over 40 postdocs.

To apply, submit a motivation letter, your cv, a description of your
research experience and interest, and the names and contact information
of 2-3 referees. The application material must be uploaded through the
UNIL online recruitment platform at http://bit.ly/2BFXdUP (you may have
to create an account in the system first). For questions concerning the
position, please send an email to Tadeusz.Kawecki@unil.ch. The review of
applications will start on December 15 and will continue until a
suitable candidate is found.


Tadeusz Kawecki <tadeusz.kawecki@unil.ch>

Oferta de voluntariado en un acuario danés

KATTEGATCENTRET – Acuario en dinamarca

Días:01/09/2018-01/09/2019

Lugar: Grenå, Dinamarca

Número de Voluntarios: 1

Mandar la solicitud antes del 3 de enero 2018

Número de proyecto: PIC 946375651 Ref numb. 2014-1-DK01-KA110-004035


Proyecto de Servicio de Voluntariado Europeo para jóvenes de entre 18 y 30 años de nacionalidad/residencia española. Están todos los gastos cubiertos. Gastos de Viaje, alojamiento, manutención, dinero de bolsillo, seguro médico y de accidentes y curso de idiomas.

El alojamiento y manutención se realizará en una familia danesa.


El acuario Kattegatcentre es un lugar donde experimentar el océano y su vida animal. Los visitantes obtienen una experiencia única y nuevos conocimientos sobre el mundo oceánico. En el acuario hay todo tipo de especies marinas: bacalao de las costas danesas, cangrejos y langostas del Mar del Norte, tiburones y rayas de los océanos tropicales, focas y especies de agua dulce.


Se realizan talleres escolares con el fin de apoyar y profundizar las enseñanzas en biología de las escuelas, desde escuelas primarias hasta instituciones de educación superior. Anualmente se ofrece formación a 13.000 niños.


El voluntario aprenderá sobre la vida de los animales marinos y los ecosistemas, así como del mantenimiento un acuario. Aprenderá a promover el conocimiento científico. Colaborará en numerosas actividades: construcción de nuevos acuarios, limpieza y mantenimiento de los acuarios existentes, alimentación y cuidado de peces y otros animales marinos, y cualquier otra actividad que se realice.


Más información en: http://www.kattegatcentret.dk/


Si te interesa este proyecto mándanos un correo a evs@all2help.org y te mandaremos el documento de solicitud.

7 de diciembre de 2017

Voluntariado de investigación de biología marina en Dinamarca

Centro de investigación marina de la Universidad de Kerteminde

Días:01/09/2018-01/09/2019

Número de Voluntarios: 2

Mandar la solicitud antes del 3 de enero 2018

Número de proyecto: PIC 999904616



Proyecto de Servicio de Voluntariado Europeo para jóvenes de entre 18 y 30 años de nacionalidad/residencia española. Están todos los gastos cubiertos. Gastos de Viaje, alojamiento, manutención, dinero de bolsillo, seguro médico y de accidentes y curso de idiomas.

El alojamiento y manutención se realizará en una familia danesa.



El Centro de Investigación Biológica Marina en Kerteminde es parte del Departamento de Biología de la Universidad del Sur de Dinamarca. Kerteminde está en la isla Fyn, una isla en el medio de Dinamarca. Desde la isla se accede fácilmente a cualquier parte del país.



El centro es internacionalmente conocido. Se enfoca en todos los aspectos de la investigación marina, tanto en labor de campo como de laboratorio. El centro tiene proyectos enfocados en esponjas, medusas, mejillones azules y otros animales que se alimentan por filtración; así como laboratorios de bioacústica donde hay focas grises, cormoranes y marsopas.



Se buscan voluntarios con educación en biología o psicología o experiencia con animales. Deben de tener un alto grado de motivación para el aprendizaje y ética de trabajo.



Las labores de voluntariado incluirán:

· Sesiones diarias de investigación y entrenamiento con 2 focas grises, 2 cormoranes y 2 tortugas

· Ayuda en el cuidado diario de los animales y cría de los animales

· Limpieza y mantenimiento de las áreas e instalaciones de los animales

Se ofrecerá formación a los voluntarios relacionado con el aprendizaje del comportamiento de los animales, la modificación del comportamiento y el entrenamiento de los animales, así como en los paradigmas de bioacústica, psicofísica y prueba de paradigmas.



Más información en:

http://www.sdu.dk/Om_SDU/Institutter_centre/I_Biologi/Forskning/Feltstationer/Marinbiologisk +Forskningscenter





Si te interesa este proyecto mándanos un correo a evs@all2help.org y te mandaremos el documento de solicitud.

6 de diciembre de 2017

Voluntariado con marsopas y focas en Dinamarca


FJORD&BÆLT – Proyecto con marsopas y focas

Días:01/08/2018-01/08/2019

Número de Voluntarios: 2

Mandar la solicitud antes del 3 de enero 2018

Proyecto Nº: PIC 943848413 / 943841720 – Ref number 2013-DK-24

Proyecto de Servicio de Voluntariado Europeo para jóvenes de entre 18 y 30 años de nacionalidad/residencia española. Están todos los gastos cubiertos. Gastos de Viaje, alojamiento, manutención, dinero de bolsillo, seguro médico y de accidentes y curso de idiomas.

El alojamiento y manutención se realizará en una familia danesa.

Fjord & Bælt es un centro de investigación sobre la vida marina en las aguas de Dinamarca. Es uno de los pocos lugares del mundo donde es posible conocer de cerca la vida de los animales marinos. Todos los días se alimentan y entrena a tres marsopas: Eigil, Freja y Sif y a tres divertidas focas: Svante, Tulle y Naja. Los animales viven y nadan en cuencas naturales que se abastecen continuamente con agua de mar del fiordo y del estrecho. Al centro se acercan aproximadamente 60.000 visitantes al año.



Fjord & Bælt cuenta con 12 empleados a tiempo completo y un grupo de voluntarios y trabajadores a tiempo parcial y en prácticas. El departamento de investigación esta formado por un líder de departamento danés y dos entrenadores suecos. Personal en prácticas y voluntarios daneses y extranjeros ayudan en todas las tareas diarias, como observar, entrenar, alimentar y jugar con las marsopas y focas.



Más información

http://www.fjordbaelt.dk/index.php/en/

www.facebook.com/fjordogbaelt


Si te interesa este proyecto mándanos un correo a evs@all2help.org y te mandaremos el documento de solicitud.

5 de diciembre de 2017

2 cursos avanzados para biólogos, organizados por Transmitting Science

El equipo de Transmitting Science, gente muy maja, ha ofrecido reducir los precios de estos cursos un 20% para todos los suscriptores de Bioblogia.net. ¡Únete aquí si aún no estás en la lista! (y no olvides mencionarlo cuando te matricules en algún curso).

20 de noviembre de 2017

Prácticas de conservación de aves (Wisconsin, USA)

The International Crane Foundation (ICF) is seeking to fill four Crane and Conservation Naturalist Intern positions in 2018.

ICF Background:
ICF is a leader in the conservation of the world's 15 crane species and is dedicated to providing experience, knowledge, and inspiration to involve people in resolving threats to cranes and the ecosystems vital to their long-term survival. Although ICF has projects all around the world the headquarters is located in Baraboo, WI one hour north of Madison, WI. ICF is open to the public every day from April 15th to October 31st each year and all of the world’s 15 crane species are on live-display at our facility. For more information, please visit our website at www.savingcranes.org

Description:
ICF Crane and Conservation Naturalist Interns will gain valuable hands-on experience working with the Conservation Education Department and will:


· Develop and lead daily interpretive tours at ICF for visiting schools, community organizations, private groups, and the general public.

· Assist in the completion of one or several projects related to the goals, work plan, and objectives of the ICF Conservation Education Department (e.g. help design and develop self-guided written or audio media; write, film and edit short films about ICF’s work; create, test, and evaluate interpretive programs; design interpretive wayside panels; assist in managing ICF’s volunteer program; organize and implement on-site events; or research policy related projects and initiatives, etc.)

· Plan, organize, market and execute one or more onsite events (Mother’s Day, Whooping Crane Day, Cranes of the World Festival, Good Neighbor Day).

· Provide outreach programs for local schools, civic groups, housing facilities, parks and festivals.

· Interact and assist with the sale of admission tickets, gift shop merchandise, annual memberships, and overall ICF site orientation on a daily basis.

· Conduct duties associated with opening/closing the visitor center, exhibits, and gift shop on a daily basis.

· Achieve experience planning, designing, and evaluating interpretive programs and written materials.

· Learn about ICF project initiatives related to crane ecology, behavior, and husbandry; field conservation and ecology; and ecosystem restoration techniques and processes.

· Have the opportunity to volunteer with other departments and participate in job shadow experiences at ICF.

· Meet and work with a variety of international colleagues and professional staff at ICF.





ICF’s Crane and Conservation Naturalist Internship begins February 28th, 2018 and runs through November 16th, 2018. A taxable $565/month stipend and comfortable on-site housing accommodations are provided at no charge. Applicants should be prepared to live in a co-ed communal living situation and be able to work outdoors everyday in all weather conditions found in Wisconsin. Naturalist interns will work weekends and will have two consecutive days off during the work week. The ICF campus is set in a rural Wisconsin setting at the edge of Wisconsin’s beautiful Driftless area and is adjacent to state parks and many nature oriented activity areas. All applicants must be eligible to work in the United States at the time they apply. Candidates without a work visa must obtain one before they will be considered for an internship. ICF is an Equal Opportunity Employer.



Qualifications:
B.A. or B.S. preferred. Students from all disciplines are welcome to apply, however studies relating to wildlife conservation, education, or biology are preferred. The applicant should have exceptional customer service, proficient public speaking skills and a strong desire to teach diverse audiences in a non-formal setting. Candidates should demonstrate an interest/background in the fields of interpretation, environmental education, conservation biology, ornithology, education, digital marketing, graphic design, film/documentary production, and other related fields.



Application Procedure:
Applicants should send a one page cover letter, resume (no more than two pages), and contact information for three references to:



icfinternships@savingcranes.org Please put Interpretive Program in the subject line
Attn: Andy Bingle, Interpretive Program Manager
Phone: 608-356-9462 ext.108



Positions are open until filled. Job opening closes January 15th.

19 de noviembre de 2017

Postdoc sobre efectos de cambio climático en peces (Australia)

*ARC Research Associate (post-doc)*

*Job no: 497658*

*Work type: Fixed term - Full-time*

*Location: Adelaide*

*Categories: Faculty of Sciences, Level A*

* *Prestigious international university*
* *Research Associate*
* *Modelling climate change effects on Australian fish and fisheries
species*

The University of Adelaide is one of Australia's leading Group of Eight, research-intensive universities and is consistently ranked among the top 1% of universities in the world. Established in 1874, it is Australia's third oldest university with a strong reputation for preparing educated
leaders and delivering research outcomes that contribute to local, national and global wellbeing.

The Faculty of Sciences is one of five faculties at the University of
Adelaide. As the first university in Australia to grant degrees in
science (1882), science has long been at the cornerstone of the
institution and this continues today.

The School of Biological Sciences is one of four schools in the Faculty
of Sciences. Located at the University's North Terrace campus, the
school consists of approximately 600 people including research, teaching
and professional staff, and students in honours and research. The school
was formed in 2015 to coordinate and consolidate the University's
cutting edge and world-class research and teaching in Ecology &
Environmental Science; Genetics & Evolution; and Molecular & Cellular
Biology.

_Funding has been obtained from the Australian Research Council for a
multi-year project studying the effects of climate-driven range
extensions of tropical coral reef fishes on temperate Australian coastal
ecosystems. We are seeking a Research Associate with excellent
quantitative skills to analyse a long-term fish population dataset using
coupled niche-population models._

The project is a collaborative project between the University of
Adelaide, University of Technology Sydney, the University of the
Sunshine Coast, and Flinders University. The School of Biological
Sciences has strong expertise across the disciplines of marine ecology
and global change biology. Successful candidates will join a dynamic
group of students and academics working on climate change at the School
and interact significantly with the project’s chief investigators.

*Salary*: Level A; $83,307-$89,425 per annum.

*Superannuation*: An employer contribution of 9.5% applies

*Term of position*: This fixed-term contract is available February 2018
to December 2019

*Position requirements*

To be successful you should have:

1. A PhD with developed experience in numerical analysis and various
modelling techniques.

2. Demonstrated experience and proficiency in programing language, this
should at least include R, but familiarity with MatLab, Python, C or
similar is also preferred.

3. Demonstrated ability to publish in high-impact scientific journals,
and present research at international conferences. You should be fluent
in English, and have a range of scientific articles as first author in
high-impact journals (indexed in Web of Science).

4. Strong written and oral communication skills in English with the
ability to liaise, collaborate and interact with a wide range of
national and international scientific researchers.

5. Ability to work effectively as part of a multi-disciplinary team.

6. Demonstrated experience in ecological research, in particular related
to climate change and population dynamics.

7. Capacity to meet deadlines and complete manuscripts in a timely manner.

8. Ability to use initiative to solve problem in non-routine situations.

Additional desired criteria are:

9. A keen interest in marine ecology, climate ecology, species
biogeography and population dynamics.

10. Knowledge of Australian marine ecosystems and species.

Please address and upload your responses to the selection criteria
within the online application
(_http://careers.adelaide.edu.au/cw/en/job/497658/arc-research-associate_).
This should include CV, list of publications and a list of 3 potential
referees. If you have any queries regarding this position, please
contact Prof. Ivan Nagelkerken:

Email – ivan.nagelkerken@adelaide.edu.au
http://researchers.adelaide.edu.au/profile/ivan.nagelkerken

Please note if the position description/selection criteria link is not
appearing, you will need to view on another device.

*Closing date: 10 December 2017*

*/The University of Adelaide is an Equal Employment Opportunity
employer. Women, Aboriginal and Torres Strait Islander people who meet
the requirements of this position are strongly encouraged to apply./*

--
most recent papers:
Ocean life breaking rules by building shells in acidic extremes. Curr Biol (http://www.cell.com/current-biology/abstract/S0960-9822(17)31097-7)
Impacts of near-future ocean acidification and warming on the shell mechanical and geochemical properties of gastropods from intertidal to subtidal zones. Env Sci Tech (http://pubs.acs.org/doi/abs/10.1021/acs.est.7b02359)
Species Interactions Drive Fish Biodiversity Loss in a High-CO2 World. Curr Biol (http://www.sciencedirect.com/science/article/pii/S096098221730725X)
Boosted food web productivity through ocean acidification collapses under warming. Glob Change Biol (http://onlinelibrary.wiley.com/doi/10.1111/gcb.13699/abstract)


Prof. Ivan Nagelkerken

Southern Seas Ecology Laboratories, Darling Building, DX 650 418
School of Biological Sciences, The University of Adelaide
Adelaide SA 5005, Australia

18 de noviembre de 2017

Dos doctorados en neuro y bio molecular (Alemania)

The German Center for Neurodegenerative Diseases (DZNE) investigates the causes of diseases of the nervous system and develops strategies for prevention, treatment and care. It is an institution within the Helmholtz Association of German Research Centers with nine sites across Germany (Berlin, Bonn, Dresden, Göttingen, Magdeburg, Munich, Rostock/Greifswald, Tübingen and Witten). The DZNE cooperates closely with universities, their clinics and other research facilities.

The DZNE in Bonn offers two positions as

PhD student (f/m) - Code 1514/2017/11

within Dr. Daniele Bano and Prof. Paolo Salomoni research groups.

Description: The groups of Dr. Daniele Bano and Prof. Paolo Salomoni study the interplay between epigenetic plasticity, mitochondrial function and metabolism in aging and brain pathophysiology. Dr. Bano’s group has previously elucidated novel mitochondria-dependent molecular cascades that contribute to cell death and neuronal dysfunction (Sendoel A. et al, 2014; Gioran A. et al, 2014; Meyer K. et al, 2015). Moreover, we have recently demonstrated the relevance of replication-independent histone H3.3 variant in controlling the epigenetic landscape that promotes pro-survival signaling pathways (Piazzesi A. et al, 2016) and in regulation of activity-dependent transcription in neurons (Michod D. et al, 2012). Prof. Salomoni’s group has recently shown that a brain-cancer associated mutation in the same histone variant disrupts brain development and promotes high-grade glioma in mice (Pathania M. et al, in press). We are interested in identifying molecular mechanisms that regulate nucleosome plasticity and may contribute to neurodegenerative processes during aging. In this regard, we offer the following two jointly supervised projects:

1) Role of the SWI/SNF complex in the nervous system. Using an array of single and double knockout mice, we have elucidated the unique biological role of the BCL7A-containing SWI/SNF/BAF complex in the epigenetic maintenance of neuronal function (Wischhof L. et al, ms under revision; Wischhof L. et al, ms submitted). We will test the contribution of the SWI/SNF complex in age-related metabolic dysfunction and whether metabolic insults accelerate neurodegenerative processes in mice with aberrant nucleosome plasticity.

2) H3.3 and its chaperones in the nervous system. This work will build on our previous studies on H3.3 in nematode lifespan regulation, and will specifically explore how H3.3 loading is regulated downstream to pro-longevity signaling pathways and what is its contribution to chromatin and transcriptional plasticity using mouse as a model system.

Your profile: We are looking for a highly motivated and science-driven person with a recent M.sc. degree or equivalent qualification; a background in neuroscience or related areas of biology (e.g., neurobiology, molecular biology, (epi)-genetics or behavioral neuroscience); solid hands-on experience in laboratory animal experimentation (e.g. mouse colony management, handling, perfusion and in-vivo experiments (FELASA B level) or molecular biology (e.g. protein/RNA extraction, western blotting, PCR); good communication skills and the ability for teamwork. Additional expertise in the following areas would be a plus: histology: tissue preparation, staining (histochemistry, immunofluorescence); confocal and STED microscopy and imaging analysis; in-vitro cell culture models (especially iPSC).

We offer:

An interesting and challenging research structure that works on the future topics of health research
An international environment characterized by a strong focus on science and research
A high potential for the individual development of our employees
Targeted personnel development
The position is available starting from 8th January 2018 for 3 years
Employment, payment and social benefits are consistent with those at other research institutes

You will obtain special skills and knowledge for your scientific qualification during your activities at DZNE. The DZNE is an equal opportunity employer. It especially welcomes and encourages disabled individuals to apply.

Interested candidates should send their application including a CV and references via the following link:

jobs.dzne.de/en/jobs/97/form

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