PhD Position in Ecological Genomics of Convergent Adaptation to Whole Genome Duplication
Location: Prague, Czech Republic
Organization: Group of Ecological Genomics (Filip Kolár), Department of Botany, Faculty of Science, Charles University, and Institute of Botany, Czech Academy of Sciences
Contract Type: PhD position (start date negotiable)
Main Description:
When and under which circumstances does evolution repeat itself? Evolution is driven by a combination of deterministic forces and stochasticity, whose relative importance remains a matter of debate. Knowing how predictable evolution is can provide insights into predictive evolution of crops, pathogens or species under climate change.
This project will address genomic basis and phenotypic consequences of repeated genome evolution in response to whole genome duplication (WGD). WGD is a dramatic mutation that may provide evolutionary opportunity but also imposes severe stresses associated with cell division and homeostasis, to which a nascent polyploid has to adapt.
By leveraging the natural diversity of Brassicaceae plants which repeatedly underwent changes in ploidy level, the project aims at uncovering general mechanisms determining which portion of their genomes evolves in a predictable manner. The successful candidate will conduct detailed analyses of evolutionary history and genomic basis of WGD adaptation in several species using already available short- and long-read genome-wide data.
Development of spin-off projects in ecological genomics of selected species, participation in cytogenetic assays and/or additional field sampling campaigns in the Balkans is possible. The project builds on previous research in wild Arabidopsis (Konecná et al. 2021 Nat. Comms., Bohutínská et al. 2021 PNAS and 2024 Plos Gen, Vlcek et al. 2025 PNAS) but will extend well beyond this system in order to discern generality.
The project will involve close collaboration with other lab members and national and international project partners, including collaborators at SLU Uppsala (Levi Yant) and University of Calgary (Sam Yeaman).
Requirements:
- Strong motivation for interdisciplinary research at the border of evolutionary biology and population genomics
- MSc degree in Biology or related fields (must be obtained by early fall 2026 at the latest)
- Good spoken and written English; communication at the Department is fully in English
Desirable (not required):
- Experience with evolutionary history reconstruction/biosystematics
- Background in population genetics
- Experience with processing high-throughput sequence data
Benefits/Conditions:
- Creative and supporting atmosphere in an international team
- Membership to an international, diverse PhD student community at Department of Botany
- Additional interdisciplinary experience through international collaboration in polyploid evolutionary genomics and statistical genomics
- Competitive salary covered
- Fully covered health insurance and contribution to the social security system
- Support for establishment of foreign employees via the Staff Welcome Center of the University
- Work in the historical center of Prague, a vibrant cultural city
How to Apply:
Submit your CV (including contact details for two referees) and an approximately half-page motivation letter as a single PDF file via the registration form: https://forms.gle/LbDvGuSGWJBHvcJw9
Review of applications will begin on March 15, 2026 and will continue until the position has been filled.
For additional questions, contact: Filip Kolár (filip.kolar@natur.cuni.cz)
Further information: https://www.plantecologicalgenomics.cz/