PhD Opportunity: Evolution Following Whole Genome Duplication - A Comparative Investigation of Plant and Animal Genomes
Institution: University of Edinburgh
Project Start Date: 2025
Project Background
Whole genome duplication (WGD), or polyploidy, is an extreme mutation with significant evolutionary consequences. This phenomenon has been observed across multiple eukaryotic lineages, playing a critical role in events such as the emergence of seed plants and vertebrates. Following WGD, duplicated genomes stabilize through a process known as rediploidisation, where some duplicated genes are lost while others evolve new functions, driving phenotypic diversity and species evolution.
Despite the recognized importance of WGD, much remains unknown about the mechanisms and outcomes of rediploidisation. This PhD project aims to bridge the gap between plant and animal WGD research by integrating concepts and methods across both fields, advancing our understanding of evolutionary processes.
Consortium Context
This PhD is part of a 4-year BBSRC-funded consortium project involving leading UK institutions, including the Universities of Bath, Bristol, and Oxford, Royal Botanic Gardens Kew, and the Wellcome Sanger Institute, with additional international collaborators. The successful candidate will collaborate within this dynamic network, with opportunities to attend international conferences and receive advanced training in genomics, phylogenetics, and bioinformatics.
Candidate Requirements
We seek an accomplished student with:
- Proven interests in genetics or evolutionary biology.
- Existing experience in bioinformatics.
Application Instructions
Submit the following by Monday 16th December 2024, at 12 noon:
- Statement of Interest.
- Full CV, including names and contact details (with email addresses) of two academic referees.
Email applications to: RDSVS.Studentship.Applications@ed.ac.uk
In the covering letter, clearly state:
- The project title: Evolution following whole genome duplication - A comparative investigation of plant and animal genomes.
- The supervisor's name.
Informal Enquiries
For informal discussions about the project, contact:
- Dr. Dan Macqueen: daniel.macqueen@roslin.ed.ac.uk
Additional Information
The University of Edinburgh is committed to equality, diversity, and inclusion.
